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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Filamin A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FLNA
Gene Synonyms
FLN
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Gene Full Name
filamin A
Gene Summary
The protein encoded by this gene is an
actin-binding protein that crosslinks actin filaments and links actin
filaments to membrane glycoproteins. The encoded protein is involved in
remodeling the cytoskeleton to effect changes in cell shape and migration. This
protein interacts with integrins, transmembrane receptor complexes, and
second messengers. Defects in this gene are a cause of several syndromes,
including periventricular nodular heterotopias (PVNH1, PVNH4),
otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD),
Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal
pseudoobstruction (CIIPX). Two transcript variants encoding different
isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
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Molecular
Weight(MW)
281 kDa
Cellular
Localizatio
Cell projection, Cytoplasm, Cytoskeleton
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
FMD
MNS
OPD
ABPX
CSBS
CVD1
FGS2
FLN1
NHBP
OPD1
OPD2
XLVD
XMVD
FLN-A
ABP-280
·
WB
Western blot analysis using Filamin A antibody against Hela(1), A549(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using Filamin A antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using Filamin A antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |