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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-TAK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MAP3K7
Gene Synonyms
CSCF
More
Gene Full Name
mitogen-activated protein kinase kinase
kinase 7
Gene Summary
The protein encoded by this gene is a
member of the serine/threonine protein kinase family. This kinase mediates
the signaling transduction induced by TGF beta and morphogenetic protein
(BMP), and controls a variety of cell functions including transcription
regulation and apoptosis. In response to IL-1, this protein forms a kinase
complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is
required for the activation of nuclear factor kappa B. This kinase can also
activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response
to environmental stresses. Four alternatively spliced transcript variants
encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
More
Molecular
Weight(MW)
67 kDa
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
FMD2
TAK1
MEKK7
TGF1a
·
WB
Western blot analysis using TAK1 antibody against Jurkat(1), HepG2(2), MCF-7(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using TAK1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using TAK1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |