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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-INSR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
INSR
Gene Synonyms
HHF5
Gene Full Name
insulin receptor
Gene Summary
This gene encodes a member of the
receptor tyrosine kinase family of proteins. The encoded preproprotein is
proteolytically processed to generate alpha and beta subunits that form a
heterotetrameric receptor. Binding of insulin or other ligands to this receptor
activates the insulin signaling pathway, which regulates glucose uptake and
release, as well as the synthesis and storage of carbohydrates, lipids and
protein. Mutations in this gene underlie the inherited severe insulin
resistance syndromes including type A insulin resistance syndrome, Donohue
syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in
multiple transcript variants. [provided by RefSeq, Oct 2015]
Hide
Molecular
Weight(MW)
156 kDa
Source
Rabbit
Cellular
Localizatio
Cell membrane, Endosome, Lysosome,
Membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
CD220
·
WB
Western blot analysis using INSR antibody against A549(1), Hela(2), A431(3), MCF-7(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using INSR antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using INSR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |