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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-BCL2A1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
BCL2A1
Gene Synonyms
GRS
More
Gene Full Name
BCL2 related protein A1
Gene Summary
This gene encodes a member of the BCL-2
protein family. The proteins of this family form hetero- or homodimers and
act as anti- and pro-apoptotic regulators that are involved in a wide variety
of cellular activities such as embryonic development, homeostasis and
tumorigenesis. The protein encoded by this gene is able to reduce the release
of pro-apoptotic cytochrome c from mitochondria and block caspase activation.
This gene is a direct transcription target of NF-kappa B in response to
inflammatory mediators, and is up-regulated by different extracellular
signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF),
CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a
cytoprotective function that is essential for lymphocyte activation as well
as cell survival. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by RefSeq, Jul
2008]
More
Source
Rabbit
Cellular
Localizatio
Cytoplasm
Application
ICC/IF:1:100-1:500
ACC1
ACC2
BFL1
ACC-1
ACC-2
HBPA1
BCL2L5
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using BCL2A1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using BCL2A1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:1000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |