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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Smad3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMAD3
Gene Synonyms
LDS3
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Gene Full Name
SMAD family member 3
Gene Summary
The SMAD family of proteins are a group
of intracellular signal transducer proteins similar to the gene products of
the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C.
elegans gene Sma. The SMAD3 protein functions in the transforming growth
factor-beta signaling pathway, and transmits signals from the cell surface to
the nucleus, regulating gene activity and cell proliferation. It also
functions as a tumor suppressor. Mutations in this gene are associated with
aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by
RefSeq, Nov 2019]
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Molecular
Weight(MW)
48 kDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Nucleus.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
LDS1C
MADH3
JV15-2
HSPC193
HsT17436
·
WB
Western blot analysis using Smad3 antibody against PANC-1(1), A431(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using Smad3 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using Smad3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |