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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Fbx32 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FBXO32
Gene Synonyms
Fbx32
Gene Full Name
F-box protein 32
Gene Summary
This gene encodes a member of the F-box
protein family which is characterized by an approximately 40 amino acid
motif, the F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which
function in phosphorylation-dependent ubiquitination. The F-box proteins are
divided into 3 classes: Fbws containing WD-40 domains, Fbls containing
leucine-rich repeats, and Fbxs containing either different protein-protein
interaction modules or no recognizable motifs. The protein encoded by this
gene belongs to the Fbxs class and contains an F-box domain. This protein is
highly expressed during muscle atrophy, whereas mice deficient in this gene
were found to be resistant to atrophy. This protein is thus a potential drug
target for the treatment of muscle atrophy. Alternative splicing results in
multiple transcript variants encoding different isoforms. [provided by
RefSeq, Jun 2011]
More
Molecular
Weight(MW)
42 kDa, 25kDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
MAFbx
·
WB
Western blot analysis using Fbx32 antibody against PANC-1(1), A431(2),HEK293(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded colon cancer tissues using Fbx32 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using Fbx32 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |