Product Profile

Product Name	Anti-EDG1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFWB
	WB:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	S1PR1
Gene Synonyms	EDG1 S1P1 CD363 ECGF1 EDG-1 CHEDG1 D1S3362 Hide
Gene Full Name	sphingosine-1-phosphate receptor 1
Gene Summary	The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Hide
Molecular Weight(MW)	43 kDa
Source	Rabbit
Cellular Localizatio	Cell membrane

Application

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WB

Western blot analysis using EDG1 antibody against A549(1),MCF-7(2) cell lysate.

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ICC/IF

Immunofluorescence analysis of MG-63 cells using EDG1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.