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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CD13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ANPEP
Gene Synonyms
APN
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Gene Full Name
alanyl aminopeptidase, membrane
Gene Summary
Aminopeptidase N is located in the
small-intestinal and renal microvillar membrane, and also in other plasma
membranes. In the small intestine aminopeptidase N plays a role in the final
digestion of peptides generated from hydrolysis of proteins by gastric and
pancreatic proteases. Its function in proximal tubular epithelial cells and
other cell types is less clear. The large extracellular carboxyterminal
domain contains a pentapeptide consensus sequence characteristic of members
of the zinc-binding metalloproteinase superfamily. Sequence comparisons with
known enzymes of this class showed that CD13 and aminopeptidase N are
identical. The latter enzyme was thought to be involved in the metabolism of
regulatory peptides by diverse cell types, including small intestinal and
renal tubular epithelial cells, macrophages, granulocytes, and synaptic
membranes from the CNS. This membrane-bound zinc metalloprotease is known to
serve as a receptor for the HCoV-229E alphacoronavirus as well as other
non-human coronaviruses. This gene has also been shown to promote
angiogenesis, tumor growth, and metastasis and defects in this gene are
associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr
2020]
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Source
Rabbit
Cellular
Localizatio
Cell membrane
Application
CD13
LAP1
P150
PEPN
GP150
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CD13 antibody with DAB staining.
Application Notes |
IHC:1:200-1:1000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |