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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Cdk5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CDK5
Gene Synonyms
LIS7
Gene Full Name
cyclin dependent kinase 5
Gene Summary
This gene encodes a proline-directed
serine/threonine kinase that is a member of the cyclin-dependent kinase
family of proteins. Unlike other members of the family, the protein encoded
by this gene does not directly control cell cycle regulation. Instead the
protein, which is predominantly expressed at high levels in mammalian
postmitotic central nervous system neurons, functions in diverse processes
such as synaptic plasticity and neuronal migration through phosphorylation of
proteins required for cytoskeletal organization, endocytosis and exocytosis,
and apoptosis. In humans, an allelic variant of the gene that results in
undetectable levels of the protein has been associated with lethal autosomal
recessive lissencephaly-7. Alternative splicing results in multiple
transcript variants. [provided by RefSeq, May 2015]
More
Molecular
Weight(MW)
33 kDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm, Nucleus, Cell membrane,
Perikaryon, Cell junction
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
PSSALRE
·
WB
Western blot analysis usingCdk5 antibody against HEK293(1), A549(2),HepG2(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using Cdk5 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using Cdk5 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |