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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-TSG101 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TSG101
Gene Synonyms
TSG10
Gene Full Name
tumor susceptibility 101
Gene Summary
The protein encoded by this gene belongs
to a group of apparently inactive homologs of ubiquitin-conjugating enzymes.
The gene product contains a coiled-coil domain that interacts with stathmin,
a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play
a role in cell growth and differentiation and act as a negative growth
regulator. In vitro steady-state expression of this tumor susceptibility gene
appears to be important for maintenance of genomic stability and cell cycle
regulation. Mutations and alternative splicing in this gene occur in high
frequency in breast cancer and suggest that defects occur during breast
cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
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Molecular
Weight(MW)
44 kDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm, Cytoskeleton, Endosome,
Membrane, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
VPS23
·
WB
Western blot analysis using TSG101 antibody against NIH3T3(1),HEK293(2),A549(3),HepG2,(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TSG101 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using TSG101 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |