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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-SIRT1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SIRT1
Gene Synonyms
SIR2
Gene Full Name
sirtuin 1
Gene Summary
This gene encodes a member of the sirtuin
family of proteins, homologs to the yeast Sir2 protein. Members of the
sirtuin family are characterized by a sirtuin core domain and grouped into
four classes. The functions of human sirtuins have not yet been determined;
however, yeast sirtuin proteins are known to regulate epigenetic gene
silencing and suppress recombination of rDNA. Studies suggest that the human
sirtuins may function as intracellular regulatory proteins with
mono-ADP-ribosyltransferase activity. The protein encoded by this gene is
included in class I of the sirtuin family. Alternative splicing results in
multiple transcript variants. [provided by RefSeq, Dec 2008]
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Molecular
Weight(MW)
82 kDa, 120 kDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm, Mitochondrion, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
SIR2L1
SIR2alpha
·
WB
Western blot analysis using SIRT1 antibody against COS-7 (1), A549 (2), NIH3T3 (3), HepG2 (4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SIRT1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of U251 cells using SIRT1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |