![]() |
产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Caveolin-1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CAV1
Gene Synonyms
CAV1
Hide
Gene Full Name
caveolin 1
Gene Summary
The scaffolding protein encoded by this
gene is the main component of the caveolae plasma membranes found in most
cell types. The protein links integrin subunits to the tyrosine kinase FYN,
an initiating step in coupling integrins to the Ras-ERK pathway and promoting
cell cycle progression. The gene is a tumor suppressor gene candidate and a
negative regulator of the Ras-p42/44 mitogen-activated kinase cascade.
Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and
express colocalizing proteins that form a stable hetero-oligomeric complex.
Mutations in this gene have been associated with Berardinelli-Seip congenital
lipodystrophy. Alternatively spliced transcripts encode alpha and beta
isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Hide
Molecular
Weight(MW)
20 kDa
Source
Rabbit
Cellular
Localizatio
Golgi apparatus membrane. Cell membrane.
Membrane > caveola
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
CGL3
PPH3
BSCL3
LCCNS
VIP21
MSTP085
·
WB
Western blot analysis using Caveolin-1 antibody against MG-63(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using Caveolin-1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using Caveolin-1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |