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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PTPRC antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PTPRC
Gene Synonyms
LCA
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Gene Full Name
protein tyrosine phosphatase receptor
type C
Gene Summary
The protein encoded by this gene is a
member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes including
cell growth, differentiation, mitosis, and oncogenic transformation. This PTP
contains an extracellular domain, a single transmembrane segment and two
tandem intracytoplasmic catalytic domains, and thus is classified as a
receptor type PTP. This PTP has been shown to be an essential regulator of T-
and B-cell antigen receptor signaling. It functions through either direct
interaction with components of the antigen receptor complexes, or by
activating various Src family kinases required for the antigen receptor signaling.
This PTP also suppresses JAK kinases, and thus functions as a regulator of
cytokine receptor signaling. Alternatively spliced transcripts variants of
this gene, which encode distinct isoforms, have been reported. [provided by
RefSeq, Jun 2012]
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Molecular
Weight(MW)
147 kDa(Observed:120
kDa)
Source
Rabbit
Cellular
Localizatio
Membrane,Membrane raft
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
LY5
B220
CD45
L-CA
T200
CD45R
GP180
·
WB
Western blot analysis using PTPRC antibody against A549(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded tonsil tissues using PTPRC antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using PTPRC antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |