Product Profile

Product Name	Anti-RAGE antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	AGER
Gene Synonyms	HSPA8 HSP7C LAP1 HSC54 HSC70 HSC71 HSP71 HSP73 LAP-1 NIP71 HEL-33 HSPA10 HEL-S-72p Hide
Gene Full Name	advanced glycosylation end-product specific receptor
Gene Summary	The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011] Hide
Molecular Weight(MW)	43 kDa
Source	Rabbit
Cellular Localizatio	Secreted and Cell membrane

Application

·

WB

Western blot analysis using RAGE antibody against A549 (1),HepG2 (2), A431(3), Hela (4) cell lysate.

·

IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using RAGE antibody with DAB staining.

·

ICC/IF

Immunofluorescence analysis of T24 cells using RAGE antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

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