Product Profile

Product Name	Anti-RhoA antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHC
	IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	RHOA
Gene Synonyms	ARHA ARH12 RHO12 EDFAOB RHOH12 Hide
Gene Full Name	ras homolog family member A
Gene Summary	This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] Hide
Source	Rabbit
Cellular Localizatio	Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane

Application

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IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using RhoA antibody with DAB staining.

Application Notes

IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.