Product Profile

Product Name	Anti-PAK2 antibody
Antibody Type	Primary Antibodies
Immunogen	Recombinent Proteins

Key Feature

Clonality	Monoclonal
Isotype	IgG
Host Species	Mouse
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanRabbit
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	PAK2
Gene Synonyms	PAK65 PAKgamma
Gene Full Name	p21 (RAC1) activated kinase 2
Gene Summary	The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	58 kDa
Source	Mouse
Cellular Localizatio	Cytoplasm, Membrane, Nucleus

Application

        

WB

Western blot analysis using PAK2 antibody against A431 (1), HT1080 (2), T24 (3), HepG2 (4) and Hela (5) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using PAK2 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.