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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM642052 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Bcl-XL antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
BCL2L1
Gene Synonyms
BCL2L1
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Gene Full Name
BCL2 like 1
Gene Summary
The protein encoded by this gene belongs
to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers
and act as anti- or pro-apoptotic regulators that are involved in a wide
variety of cellular activities. The proteins encoded by this gene are located
at the outer mitochondrial membrane, and have been shown to regulate outer
mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial
membrane potential, and thus controls the production of reactive oxygen species
and release of cytochrome C by mitochondria, both of which are the potent
inducers of cell apoptosis. Alternative splicing results in multiple
transcript variants encoding two different isoforms. The longer isoform acts
as an apoptotic inhibitor and the shorter isoform acts as an apoptotic
activator. [provided by RefSeq, Dec 2015]
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Molecular
Weight(MW)
26 kDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion inner membrane,
Mitochondrion outer membrane, Mitochondrion matrix, Cytoplasmic vesicle,
Cytoplasm, Nucleus membrane.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
BCLX
BCL2L
Bcl-X
PPP1R52
BCL-XL/S
·
WB
Western blot analysis using Bcl-XL antibody against HEK293 (1), PANC-1 (2), MCF-7 (3), HepG2 (4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using Bcl-XL antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using Bcl-XL antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |