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- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-08-26
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-AIF antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AIFM1
Gene Synonyms
AIFM1； AIF
AUNX1
CMT2D
CMTX4
COWCK
DFNX5
NADMR
NAMSD
PDCD8
COXPD6
SEMDHL
Hide
Gene Full Name
apoptosis inducing factor mitochondria
associated 1
Gene Summary
This gene encodes a flavoprotein
essential for nuclear disassembly in apoptotic cells, and it is found in the
mitochondrial intermembrane space in healthy cells. Induction of apoptosis
results in the translocation of this protein to the nucleus where it affects
chromosome condensation and fragmentation. In addition, this gene product
induces mitochondria to release the apoptogenic proteins cytochrome c and
caspase-9. Mutations in this gene cause combined oxidative phosphorylation
deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as
Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth
disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and
motor-sensory defects with deafness and cognitive disability. Alternative
splicing results in multiple transcript variants. A related pseudogene has
been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Hide
Molecular
Weight(MW)
67 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion intermembrane space.
Mitochondrion inner membrane. Cytoplasm. Nucleus.
Application
·
WB
Western blot
analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AIF antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using AIF antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AIF antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AIFM1
Gene Synonyms
AIFM1； AIF
AUNX1
CMT2D
CMTX4
COWCK
DFNX5
NADMR
NAMSD
PDCD8
COXPD6
SEMDHL
Hide
Gene Full Name
apoptosis inducing factor mitochondria
associated 1
Gene Summary
This gene encodes a flavoprotein
essential for nuclear disassembly in apoptotic cells, and it is found in the
mitochondrial intermembrane space in healthy cells. Induction of apoptosis
results in the translocation of this protein to the nucleus where it affects
chromosome condensation and fragmentation. In addition, this gene product
induces mitochondria to release the apoptogenic proteins cytochrome c and
caspase-9. Mutations in this gene cause combined oxidative phosphorylation
deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as
Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth
disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and
motor-sensory defects with deafness and cognitive disability. Alternative
splicing results in multiple transcript variants. A related pseudogene has
been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Hide
Molecular
Weight(MW)
67 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion intermembrane space.
Mitochondrion inner membrane. Cytoplasm. Nucleus.
Application
·
WB
Western blot
analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AIF antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using AIF antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AIF antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AIFM1
Gene Synonyms
AIFM1； AIF
AUNX1
CMT2D
CMTX4
COWCK
DFNX5
NADMR
NAMSD
PDCD8
COXPD6
SEMDHL
Hide
Gene Full Name
apoptosis inducing factor mitochondria
associated 1
Gene Summary
This gene encodes a flavoprotein
essential for nuclear disassembly in apoptotic cells, and it is found in the
mitochondrial intermembrane space in healthy cells. Induction of apoptosis
results in the translocation of this protein to the nucleus where it affects
chromosome condensation and fragmentation. In addition, this gene product
induces mitochondria to release the apoptogenic proteins cytochrome c and
caspase-9. Mutations in this gene cause combined oxidative phosphorylation
deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as
Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth
disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and
motor-sensory defects with deafness and cognitive disability. Alternative
splicing results in multiple transcript variants. A related pseudogene has
been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Hide
Molecular
Weight(MW)
67 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion intermembrane space.
Mitochondrion inner membrane. Cytoplasm. Nucleus.
Application
·
WB
Western blot
analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AIF antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using AIF antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AIF antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AIFM1
Gene Synonyms
AIFM1； AIF
AUNX1
CMT2D
CMTX4
COWCK
DFNX5
NADMR
NAMSD
PDCD8
COXPD6
SEMDHL
Hide
Gene Full Name
apoptosis inducing factor mitochondria
associated 1
Gene Summary
This gene encodes a flavoprotein
essential for nuclear disassembly in apoptotic cells, and it is found in the
mitochondrial intermembrane space in healthy cells. Induction of apoptosis
results in the translocation of this protein to the nucleus where it affects
chromosome condensation and fragmentation. In addition, this gene product
induces mitochondria to release the apoptogenic proteins cytochrome c and
caspase-9. Mutations in this gene cause combined oxidative phosphorylation
deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as
Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth
disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and
motor-sensory defects with deafness and cognitive disability. Alternative
splicing results in multiple transcript variants. A related pseudogene has
been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Hide
Molecular
Weight(MW)
67 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion intermembrane space.
Mitochondrion inner membrane. Cytoplasm. Nucleus.
Application
·
WB
Western blot
analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AIF antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using AIF antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AIF antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AIFM1
Gene Synonyms
AIFM1； AIF
Hide
Gene Full Name
apoptosis inducing factor mitochondria
associated 1
Gene Summary
This gene encodes a flavoprotein
essential for nuclear disassembly in apoptotic cells, and it is found in the
mitochondrial intermembrane space in healthy cells. Induction of apoptosis
results in the translocation of this protein to the nucleus where it affects
chromosome condensation and fragmentation. In addition, this gene product
induces mitochondria to release the apoptogenic proteins cytochrome c and
caspase-9. Mutations in this gene cause combined oxidative phosphorylation
deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as
Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth
disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and
motor-sensory defects with deafness and cognitive disability. Alternative
splicing results in multiple transcript variants. A related pseudogene has
been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Hide
Molecular
Weight(MW)
67 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion intermembrane space.
Mitochondrion inner membrane. Cytoplasm. Nucleus.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
AUNX1
CMT2D
CMTX4
COWCK
DFNX5
NADMR
NAMSD
PDCD8
COXPD6
SEMDHL
·
WB
Western blot analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using AIF antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using AIF antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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