|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-08-23
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
ATF6A
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
·
WB
Western blot
analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-ATF6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF6
Gene Synonyms
ACHM7
Gene Full Name
activating transcription factor 6
Gene Summary
This gene encodes a transcription factor
that activates target genes for the unfolded protein response (UPR) during
endoplasmic reticulum (ER) stress. Although it is a transcription factor,
this protein is unusual in that it is synthesized as a transmembrane protein
that is embedded in the ER. It functions as an ER stress sensor/transducer,
and following ER stress-induced proteolysis, it functions as a nuclear
transcription factor via a cis-acting ER stress response element (ERSE) that
is present in the promoters of genes encoding ER chaperones. This protein has
been identified as a survival factor for quiescent but not proliferative
squamous carcinoma cells. There have been conflicting reports about the association
of polymorphisms in this gene with diabetes in different populations, but
another polymorphism has been associated with increased plasma cholesterol
levels. This gene is also thought to be a potential therapeutic target for
cystic fibrosis. [provided by RefSeq, Aug 2011]
Hide
Molecular
Weight(MW)
75 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane and
Nucleus.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
ATF6A
·
WB
Western blot analysis using ATF6 antibody against A549 (1), MCF-1 (2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using ATF6 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using ATF6 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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