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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Rb antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
RB1
Gene Synonyms
RB1;RB
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Gene Full Name
RB transcriptional corepressor 1
Gene Summary
The protein encoded by this gene is a
negative regulator of the cell cycle and was the first tumor suppressor gene
found. The encoded protein also stabilizes constitutive heterochromatin to
maintain the overall chromatin structure. The active, hypophosphorylated form
of the protein binds transcription factor E2F1. Defects in this gene are a
cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic
sarcoma. [provided by RefSeq, Jul 2008]
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Molecular
Weight(MW)
106 KDa
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
pRb
OSRC
pp110
p105-Rb
PPP1R130
p110-RB1
·
WB
Western blot analysis using Rb antibody against COS7 (1), A549 (2), PC-3 (3), A431 (4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using RB antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using RB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |