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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-DKK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
DKK1
Gene Synonyms
SK
Gene Full Name
dickkopf WNT signaling pathway inhibitor
1
Gene Summary
This gene encodes a member of the
dickkopf family of proteins. Members of this family are secreted proteins
characterized by two cysteine-rich domains that mediate protein-protein
interactions. The encoded protein binds to the LRP6 co-receptor and inhibits
beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic
development and may be important in bone formation in adults. Elevated
expression of this gene has been observed in numerous human cancers and this
protein may promote proliferation, invasion and growth in cancer cell lines.
[provided by RefSeq, Sep 2017]
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Molecular
Weight(MW)
29 KDa
Source
Rabbit
Cellular
Localizatio
Secreted
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
DKK-1
·
WB
Western blot analysis using DKK1 antibody against HepG2 (1), A431 (2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using DKK1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of T24 cells using DKK1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |