|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM642008
- 发布日期： 2024-08-23
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM642008 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
· 
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
· 
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
TLR7-like
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
·
WB
Western blot
analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TLR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TLR7
Gene Synonyms
IMD74
Gene Full Name
toll like receptor 7
Gene Summary
The protein encoded by this gene is a
member of the Toll-like receptor (TLR) family which plays a fundamental role
in pathogen recognition and activation of innate immunity. TLRs are highly
conserved from Drosophila to humans and share structural and functional
similarities. The human TLR family comprises 11 members. They recognize
pathogen-associated molecular patterns (PAMPs) that are expressed on
infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. For the recognition of structural
components in foreign microorganisms, the various TLRs exhibit different
patterns of expression as well; in this way for example, TLR-3, -7, and -8
are essential in the recognition of single-stranded RNA viruses. TLR7 senses
single-stranded RNA oligonucleotides containing guanosine- and uridine-rich
sequences from RNA viruses, a recognition occuring in the endosomes of
plasmacytoid dendritic cells and B cells. This gene is predominantly
expressed in lung, placenta, and spleen, and is phylogenetically related and
lies in close proximity to another family member, TLR8, on chromosome X.
[provided by RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
121 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Endosome.
Lysosome. Cytoplasmic vesicle > phagosome
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
TLR7-like
·
WB
Western blot analysis using TLR7 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using TLR7 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using TLR7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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