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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PCSK9 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PCSK9
Gene Synonyms
FH3
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Gene Full Name
proprotein convertase subtilisin/kexin
type 9
Gene Summary
This gene encodes a member of the
subtilisin-like proprotein convertase family, which includes proteases that
process protein and peptide precursors trafficking through regulated or
constitutive branches of the secretory pathway. The encoded protein undergoes
an autocatalytic processing event with its prosegment in the ER and is
constitutively secreted as an inactive protease into the extracellular matrix
and trans-Golgi network. It is expressed in liver, intestine and kidney
tissues and escorts specific receptors for lysosomal degradation. It plays a
role in cholesterol and fatty acid metabolism. Mutations in this gene have
been associated with autosomal dominant familial hypercholesterolemia.
Alternative splicing results in multiple transcript variants. [provided by
RefSeq, Feb 2014]
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Molecular
Weight(MW)
74 KDa
Source
Rabbit
Cellular
Localizatio
Secreted, Plasma Membrane,endoplasmic
reticulum,lysosome, cytoplasm.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
PC9
FHCL3
NARC1
LDLCQ1
NARC-1
HCHOLA3
·
WB
Western blot analysis using PCSK9 antibody against A431(1), THp-1(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using PCSK9 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using PCSK9 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |