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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-ALDH2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ALDH2
Gene Synonyms
ALDM
Gene Full Name
aldehyde dehydrogenase 2 family member
Gene Summary
This protein belongs to the aldehyde
dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme
of the major oxidative pathway of alcohol metabolism. Two major liver
isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be
distinguished by their electrophoretic mobilities, kinetic properties, and
subcellular localizations. Most Caucasians have two major isozymes, while
approximately 50% of East Asians have the cytosolic isozyme but not the
mitochondrial isozyme. A remarkably higher frequency of acute alcohol
intoxication among East Asians than among Caucasians could be related to the
absence of a catalytically active form of the mitochondrial isozyme. The
increased exposure to acetaldehyde in individuals with the catalytically
inactive form may also confer greater susceptibility to many types of cancer.
This gene encodes a mitochondrial isoform, which has a low Km for
acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing
results in multiple transcript variants encoding distinct isoforms.[provided
by RefSeq, Nov 2016]
Hide
Molecular
Weight(MW)
56 KDa
Source
Rabbit
Cellular
Localizatio
Mitochondrion matrix
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
ALDHI
ALDH-E2
·
WB
Western blot analysis using ALDH2 antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using ALDH2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of HUVEC cells using ALDH2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |