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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Cyclin D3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CCND3
Gene Synonyms
CCND3
Gene Full Name
cyclin D3
Gene Summary
The protein encoded by this gene belongs
to the highly conserved cyclin family, whose members are characterized by a
dramatic periodicity in protein abundance through the cell cycle. Cyclins
function as regulators of CDK kinases. Different cyclins exhibit distinct
expression and degradation patterns which contribute to the temporal
coordination of each mitotic event. This cyclin forms a complex with and
functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required
for cell cycle G1/S transition. This protein has been shown to interact with
and be involved in the phosphorylation of tumor suppressor protein Rb. The
CDK4 activity associated with this cyclin was reported to be necessary for
cell cycle progression through G2 phase into mitosis after UV radiation.
Several transcript variants encoding different isoforms have been found for
this gene. [provided by RefSeq, Oct 2008]
Hide
Molecular
Weight(MW)
33 KDa
Source
Rabbit
Cellular
Localizatio
Nucleus. Cytoplasm. Membrane.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using Cyclin D3 antibody against THP-1 (1), Hep G2 (2), COS-7 (3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using Cyclin D3 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of HepG2 cells using Cyclin D3 antibody(green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |