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- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-08-22
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-CD274 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CD274
Gene Synonyms
B7-H
B7H1
PDL1
PD-L1
hPD-L1
PDCD1L1
PDCD1LG1
PD1L1
Hide
Gene Full Name
CD274 molecule
Gene Summary
This gene encodes an immune inhibitory
receptor ligand that is expressed by hematopoietic and non-hematopoietic
cells, such as T cells and B cells and various types of tumor cells. The
encoded protein is a type I transmembrane protein that has immunoglobulin
V-like and C-like domains. Interaction of this ligand with its receptor
inhibits T-cell activation and cytokine production. During infection or
inflammation of normal tissue, this interaction is important for preventing
autoimmunity by maintaining homeostasis of the immune response. In tumor
microenvironments, this interaction provides an immune escape for tumor cells
through cytotoxic T-cell inactivation. Expression of this gene in tumor cells
is considered to be prognostic in many types of human malignancies, including
colon cancer and renal cell carcinoma. Alternative splicing results in
multiple transcript variants. [provided by RefSeq, Sep 2015]
Hide
Molecular
Weight(MW)
33 KDa
Source
Rabbit
Cellular
Localizatio
Cell membrane and Endomembrane system
Application
·
WB
Western blot
analysis using CD274 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CD274 antibody with DAB
staining.
· 
ICC/IF
Immunofluorescence
analysis of HEK293 cells using CD274 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CD274 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CD274
Gene Synonyms
B7-H
B7H1
PDL1
PD-L1
hPD-L1
PDCD1L1
PDCD1LG1
PD1L1
Hide
Gene Full Name
CD274 molecule
Gene Summary
This gene encodes an immune inhibitory
receptor ligand that is expressed by hematopoietic and non-hematopoietic
cells, such as T cells and B cells and various types of tumor cells. The
encoded protein is a type I transmembrane protein that has immunoglobulin
V-like and C-like domains. Interaction of this ligand with its receptor
inhibits T-cell activation and cytokine production. During infection or
inflammation of normal tissue, this interaction is important for preventing
autoimmunity by maintaining homeostasis of the immune response. In tumor
microenvironments, this interaction provides an immune escape for tumor cells
through cytotoxic T-cell inactivation. Expression of this gene in tumor cells
is considered to be prognostic in many types of human malignancies, including
colon cancer and renal cell carcinoma. Alternative splicing results in
multiple transcript variants. [provided by RefSeq, Sep 2015]
Hide
Molecular
Weight(MW)
33 KDa
Source
Rabbit
Cellular
Localizatio
Cell membrane and Endomembrane system
Application
·
WB
Western blot
analysis using CD274 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CD274 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of HEK293 cells using CD274 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CD274 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CD274
Gene Synonyms
B7-H
B7H1
PDL1
PD-L1
hPD-L1
PDCD1L1
PDCD1LG1
PD1L1
Hide
Gene Full Name
CD274 molecule
Gene Summary
This gene encodes an immune inhibitory
receptor ligand that is expressed by hematopoietic and non-hematopoietic
cells, such as T cells and B cells and various types of tumor cells. The
encoded protein is a type I transmembrane protein that has immunoglobulin
V-like and C-like domains. Interaction of this ligand with its receptor
inhibits T-cell activation and cytokine production. During infection or
inflammation of normal tissue, this interaction is important for preventing
autoimmunity by maintaining homeostasis of the immune response. In tumor
microenvironments, this interaction provides an immune escape for tumor cells
through cytotoxic T-cell inactivation. Expression of this gene in tumor cells
is considered to be prognostic in many types of human malignancies, including
colon cancer and renal cell carcinoma. Alternative splicing results in
multiple transcript variants. [provided by RefSeq, Sep 2015]
Hide
Molecular
Weight(MW)
33 KDa
Source
Rabbit
Cellular
Localizatio
Cell membrane and Endomembrane system
Application
·
WB
Western blot
analysis using CD274 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CD274 antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of HEK293 cells using CD274 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
|
Product Name |
Anti-CD274 antibody |
|
Antibody Type |
Primary Antibodies |
|
Immunogen |
Polypeptide |
Key Feature
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Host Species |
Rabbit |
|
Tested Application |
ELISAICC/IFIHCWB |
|
WB:1:200-1:2000 |
|
|
Species Reactivity |
HumanMouseRat |
|
Concentration |
1 mg/ml |
|
Purification |
Protein A |
Target Information
|
Gene Symbol |
CD274 |
|
Gene Synonyms |
B7-H Hide |
|
Gene Full Name |
CD274 molecule |
|
Gene Summary |
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] Hide |
|
Molecular Weight(MW) |
33 KDa |
|
Source |
Rabbit |
|
Cellular Localizatio |
Cell membrane and Endomembrane system |
Application
·
WB
Western blot analysis using CD274 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CD274 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of HEK293 cells using CD274 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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