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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MUC1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MUC1
Gene Synonyms
S5.7
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Gene Full Name
mucin 1, cell surface associated
Gene Summary
This gene encodes a membrane-bound
protein that is a member of the mucin family. Mucins are O-glycosylated
proteins that play an essential role in forming protective mucous barriers on
epithelial surfaces. These proteins also play a role in intracellular
signaling. This protein is expressed on the apical surface of epithelial
cells that line the mucosal surfaces of many different tissues including lung,
breast stomach and pancreas. This protein is proteolytically cleaved into
alpha and beta subunits that form a heterodimeric complex. The N-terminal
alpha subunit functions in cell-adhesion and the C-terminal beta subunit is
involved in cell signaling. Overexpression, aberrant intracellular
localization, and changes in glycosylation of this protein have been
associated with carcinomas. This gene is known to contain a highly
polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing
results in multiple transcript variants.[provided by RefSeq, Feb 2011]
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Molecular
Weight(MW)
120 KDa, 17 kDa, 30 kDa
Source
Rabbit
Cellular
Localizatio
Secreted; Cell membrane. Cytoplasm.
Nucleus.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
CVID6
TAPA1
TSPAN28
·
WB
Western blot analysis using MUC1 antibody against PANC-1 (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using MUC1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using MUC1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |