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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-p38 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MAPK14
Gene Synonyms
MK14
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Gene Full Name
mitogen-activated protein kinase 14
Gene Summary
The protein encoded by this gene is a
member of the MAP kinase family. MAP kinases act as an integration point for
multiple biochemical signals, and are involved in a wide variety of cellular
processes such as proliferation, differentiation, transcription regulation
and development. This kinase is activated by various environmental stresses
and proinflammatory cytokines. The activation requires its phosphorylation by
MAP kinase kinases (MKKs), or its autophosphorylation triggered by the
interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of
this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle
regulator CDC25B, and tumor suppressor p53, which suggest the roles of this
kinase in stress related transcription and cell cycle regulation, as well as
in genotoxic stress response. Four alternatively spliced transcript variants
of this gene encoding distinct isoforms have been reported. [provided by
RefSeq, Jul 2008]
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Molecular
Weight(MW)
41 KDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
RK
p38
CSBP
EXIP
Mxi2
CSBP1
CSBP2
CSPB1
PRKM14
PRKM15
SAPK2A
p38ALPHA
·
WB
Western blot analysis using p38 antibody against COS-7 (1), HepG2 (2), HUVEC (3), Jurkat (4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using p38 antibody with DAB staining.
ICC/IF
Immunofluorescence analysis of HEK293 cells using p38 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |