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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MMP12 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MMP12
Gene Synonyms
ME
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Gene Full Name
matrix metallopeptidase 12
Gene Summary
This gene encodes a member of the
peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this
family are involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development, reproduction, and
tissue remodeling, as well as in disease processes, such as arthritis and
metastasis. The encoded preproprotein is proteolytically processed to
generate the mature protease. This protease degrades soluble and insoluble
elastin. This gene may play a role in aneurysm formation and mutations in
this gene are associated with lung function and chronic obstructive pulmonary
disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.
[provided by RefSeq, Jan 2016]
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Molecular
Weight(MW)
54 KDa
Source
Rabbit
Cellular
Localizatio
Extracellular matrix, Secreted
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
HME
MME
MMP-12
·
WB
Western blot analysis using MMP12 antibody against A549 (1), PANC-1 (2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using MMP12 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using MMP12 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |