Product Profile

Product Name	Anti-C3C antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	C3
Gene Synonyms	ASP C3a C3b AHUS5 ARMD9 CPAMD1 HEL-S-62p Hide
Gene Full Name	complement C3
Gene Summary	Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015] Hide
Molecular Weight(MW)	187 KDa
Source	Rabbit
Cellular Localizatio	Secreted

Application

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WB

Western blot analysis using C3C antibody against K562(1), MCF-1 (2), THP-1(3) cell lysate.

        

IHC

Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using C3C antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of T24 cells using C3C antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.