|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-08-21
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-PAX5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX5
Gene Synonyms
ALL3
BSAP
Gene Full Name
paired box 5
Gene Summary
This gene encodes a member of the paired
box (PAX) family of transcription factors. The central feature of this gene
family is a novel, highly conserved DNA-binding motif, known as the paired
box. Paired box transcription factors are important regulators in early
development, and alterations in the expression of their genes are thought to
contribute to neoplastic transformation. This gene encodes the B-cell lineage
specific activator protein that is expressed at early, but not late stages of
B-cell differentiation. Its expression has also been detected in developing
CNS and testis and so the encoded protein may also play a role in neural
development and spermatogenesis. This gene is located at 9p13, which is
involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic
lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.
This translocation brings the potent E-mu enhancer of the IgH gene into close
proximity of the PAX5 promoter, suggesting that the deregulation of transcription
of this gene contributes to the pathogenesis of these lymphomas. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
42 kDa（Observed:55
kDa）
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
·
WB
Western blot
analysis using PAX5 antibody against Jurkat (1), THP-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using PAX5 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using PAX5 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PAX5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX5
Gene Synonyms
ALL3
BSAP
Gene Full Name
paired box 5
Gene Summary
This gene encodes a member of the paired
box (PAX) family of transcription factors. The central feature of this gene
family is a novel, highly conserved DNA-binding motif, known as the paired
box. Paired box transcription factors are important regulators in early
development, and alterations in the expression of their genes are thought to
contribute to neoplastic transformation. This gene encodes the B-cell lineage
specific activator protein that is expressed at early, but not late stages of
B-cell differentiation. Its expression has also been detected in developing
CNS and testis and so the encoded protein may also play a role in neural
development and spermatogenesis. This gene is located at 9p13, which is
involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic
lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.
This translocation brings the potent E-mu enhancer of the IgH gene into close
proximity of the PAX5 promoter, suggesting that the deregulation of transcription
of this gene contributes to the pathogenesis of these lymphomas. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
42 kDa（Observed:55
kDa）
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
·
WB
Western blot
analysis using PAX5 antibody against Jurkat (1), THP-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using PAX5 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using PAX5 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PAX5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX5
Gene Synonyms
ALL3
BSAP
Gene Full Name
paired box 5
Gene Summary
This gene encodes a member of the paired
box (PAX) family of transcription factors. The central feature of this gene
family is a novel, highly conserved DNA-binding motif, known as the paired
box. Paired box transcription factors are important regulators in early
development, and alterations in the expression of their genes are thought to
contribute to neoplastic transformation. This gene encodes the B-cell lineage
specific activator protein that is expressed at early, but not late stages of
B-cell differentiation. Its expression has also been detected in developing
CNS and testis and so the encoded protein may also play a role in neural
development and spermatogenesis. This gene is located at 9p13, which is
involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic
lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.
This translocation brings the potent E-mu enhancer of the IgH gene into close
proximity of the PAX5 promoter, suggesting that the deregulation of transcription
of this gene contributes to the pathogenesis of these lymphomas. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
42 kDa（Observed:55
kDa）
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
·
WB
Western blot
analysis using PAX5 antibody against Jurkat (1), THP-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using PAX5 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using PAX5 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PAX5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX5
Gene Synonyms
ALL3
BSAP
Gene Full Name
paired box 5
Gene Summary
This gene encodes a member of the paired
box (PAX) family of transcription factors. The central feature of this gene
family is a novel, highly conserved DNA-binding motif, known as the paired
box. Paired box transcription factors are important regulators in early
development, and alterations in the expression of their genes are thought to
contribute to neoplastic transformation. This gene encodes the B-cell lineage
specific activator protein that is expressed at early, but not late stages of
B-cell differentiation. Its expression has also been detected in developing
CNS and testis and so the encoded protein may also play a role in neural
development and spermatogenesis. This gene is located at 9p13, which is
involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic
lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.
This translocation brings the potent E-mu enhancer of the IgH gene into close
proximity of the PAX5 promoter, suggesting that the deregulation of transcription
of this gene contributes to the pathogenesis of these lymphomas. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
42 kDa（Observed:55
kDa）
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
·
WB
Western blot
analysis using PAX5 antibody against Jurkat (1), THP-1 (2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded thyroid carcinoma tissues using PAX5 antibody
with DAB staining.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using PAX5 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PAX5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX5
Gene Synonyms
ALL3
Gene Full Name
paired box 5
Gene Summary
This gene encodes a member of the paired
box (PAX) family of transcription factors. The central feature of this gene
family is a novel, highly conserved DNA-binding motif, known as the paired
box. Paired box transcription factors are important regulators in early
development, and alterations in the expression of their genes are thought to
contribute to neoplastic transformation. This gene encodes the B-cell lineage
specific activator protein that is expressed at early, but not late stages of
B-cell differentiation. Its expression has also been detected in developing
CNS and testis and so the encoded protein may also play a role in neural
development and spermatogenesis. This gene is located at 9p13, which is
involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic
lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.
This translocation brings the potent E-mu enhancer of the IgH gene into close
proximity of the PAX5 promoter, suggesting that the deregulation of transcription
of this gene contributes to the pathogenesis of these lymphomas. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
42 kDa（Observed:55
kDa）
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
BSAP
·
WB
Western blot analysis using PAX5 antibody against Jurkat (1), THP-1 (2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded thyroid carcinoma tissues using PAX5 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of T24 cells using PAX5 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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