Product Profile

Product Name	Anti-alpha 1 Catenin antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	Catenin alpha-1
Gene Synonyms	MDPT2 CAP102
Gene Full Name	catenin alpha 1
Gene Summary	This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016] Hide
Molecular Weight(MW)	100 KDa
Source	Rabbit
Cellular Localizatio	Cell junction, Cell membrane, Cytoplasm, Cytoskeleton, Membrane

Application

·

WB

Western blot analysis using alpha 1 Catenin antibody against COS-7 (1), Jurkat (2), MCF-7 (3) cell lysate.

·

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using alpha 1 catenin antibody with DAB staining.

·

ICC/IF

Immunofluorescence analysis of HUVEC cells using alpha 1 catenin antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

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