|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-08-20
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-CYP3A4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP3A4
Gene Synonyms
HLP
CP33
CP34
CYP3A
NF-25
VDDR3
CYP3A3
P450C3
CYPIIIA3
CYPIIIA4
P450PCN1
Hide
Gene Full Name
cytochrome P450 family 3 subfamily A
member 4
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases that catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by glucocorticoids
and some pharmacological agents. This enzyme is involved in the metabolism of
approximately half the drugs in use today, including acetaminophen, codeine,
cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also
metabolizes some steroids and carcinogens. This gene is part of a cluster of
cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene,
CYP3A3, was thought to exist; however, it is now thought that this sequence
represents a transcript variant of CYP3A4. Alternatively spliced transcript
variants encoding different isoforms have been identified. [provided by
RefSeq, Aug 2020]
Hide
Molecular
Weight(MW)
57 KDa
Source
Rabbit
Cellular
Localizatio
Endoplasmic reticulum membrane. Microsome
membrane.
Application
·
WB
Western blot
analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
|
Product Name |
Anti-CYP3A4 antibody |
|
Antibody Type |
Primary Antibodies |
|
Immunogen |
Polypeptide |
Key Feature
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Host Species |
Rabbit |
|
Tested Application |
ELISAICC/IFIHCWB |
|
WB:1:200-1:2000 |
|
|
Species Reactivity |
HumanMouseRat |
|
Concentration |
1 mg/ml |
|
Purification |
Protein A |
Target Information
|
Gene Symbol |
CYP3A4 |
|
Gene Synonyms |
HLP Hide |
|
Gene Full Name |
cytochrome P450 family 3 subfamily A member 4 |
|
Gene Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2020] Hide |
|
Molecular Weight(MW) |
57 KDa |
|
Source |
Rabbit |
|
Cellular Localizatio |
Endoplasmic reticulum membrane. Microsome membrane. |
Application
·
WB
Western blot analysis using CYP3A4 antibody against HepG2 (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CYP3A4 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH/3T3 cells using CYP3A4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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