Product Profile

Product Name	Anti-CYP1B1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CYP1B1
Gene Synonyms	CP1B ASGD6 GLC3A CYPIB1 P4501B1 Hide
Gene Full Name	cytochrome P450 family 1 subfamily B member 1
Gene Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	61 KDa
Source	Rabbit
Cellular Localizatio	Endoplasmic reticulum, Membrane, Microsome, Mitochondrion

Application

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WB

Western blot analysis using CYP1B1 antibody against A431 (1), THP-1 (2), K562 (3) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using CYP1B1 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.