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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name |
Anti-DCX antibody |
Antibody Type |
Primary Antibodies |
Immunogen |
Polypeptide |
Key Feature
Clonality |
Polyclonal |
Isotype |
IgG |
Host Species |
Rabbit |
Tested Application |
ELISAICC/IFIHCWB |
WB:1:200-1:2000 |
|
Species Reactivity |
HumanMouseRat |
Concentration |
1 mg/ml |
Purification |
Protein A |
Target Information
Gene Symbol |
DCX |
Gene Synonyms |
DC Hide |
Gene Full Name |
doublecortin |
Gene Summary |
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010] Hide |
Molecular Weight(MW) |
41 KDa |
Source |
Rabbit |
Cellular Localizatio |
Cytoplasm |
Application
·
WB
Western blot analysis using DCX antibody against CaCo-2 cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using DCX antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using DCX antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |