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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-HEXB antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HEXB
Gene Synonyms
ENC-1AS
Gene Full Name
hexosaminidase subunit beta
Gene Summary
Hexosaminidase B is the beta subunit of
the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2
activator protein, catalyzes the degradation of the ganglioside GM2, and
other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase
is composed of two subunits, alpha and beta, which are encoded by separate
genes. Both beta-hexosaminidase alpha and beta subunits are members of family
20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead
to an accumulation of GM2 ganglioside in neurons and neurodegenerative
disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to
Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced
transcript variants encoding different isoforms have been found for this
gene. [provided by RefSeq, May 2014]
Hide
Molecular
Weight(MW)
63 KDa
Source
Rabbit
Cellular
Localizatio
Lysosome
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
HEL-248
HEL-S-111
·
WB
Western blot analysis using HEXB antibody against THp-1 (1),A431(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using HEXB antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using HEXB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |