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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name |
Anti-SHP-1 antibody |
Antibody Type |
Primary Antibodies |
Immunogen |
Polypeptide |
Key Feature
Clonality |
Polyclonal |
Isotype |
IgG |
Host Species |
Rabbit |
Tested Application |
ELISAICC/IFIHCWB |
WB:1:200-1:2000 |
|
Species Reactivity |
HumanMouseRat |
Concentration |
1 mg/ml |
Purification |
Protein A |
Target Information
Gene Symbol |
PTPN6 |
Gene Synonyms |
HCP Hide |
Gene Full Name |
protein tyrosine phosphatase non-receptor type 6 |
Gene Summary |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] Hide |
Molecular Weight(MW) |
67 KDa |
Source |
Rabbit |
Cellular Localizatio |
Cytoplasm. Nucleus. |
Application
·
WB
Western blot analysis using SHP-1 antibody against HepG2 (1), PC-3 (2), SK-OV-3 (3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded colon cancer tissues using SHP-1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH/3T3 cells using SHP-1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |