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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PKC alpha antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Applications
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKCA
Gene Synonyms
AAG6
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Gene Full Name
protein kinase C alpha
Gene Summary
Protein kinase C (PKC) is a family of
serine- and threonine-specific protein kinases that can be activated by
calcium and the second messenger diacylglycerol. PKC family members
phosphorylate a wide variety of protein targets and are known to be involved
in diverse cellular signaling pathways. PKC family members also serve as
major receptors for phorbol esters, a class of tumor promoters. Each member
of the PKC family has a specific expression profile and is believed to play a
distinct role in cells. The protein encoded by this gene is one of the PKC
family members. This kinase has been reported to play roles in many different
cellular processes, such as cell adhesion, cell transformation, cell cycle
checkpoint, and cell volume control. Knockout studies in mice suggest that
this kinase may be a fundamental regulator of cardiac contractility and
Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
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Molecular
Weight(MW)
77 KDa
Source
Rabbit
Cellular
Localizatio
Cytoplasm. Cell membrane. Nucleus.
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
PKCA
PRKACA
PKCI+/-
PKCalpha
PKC-alpha
·
WB
Western blot analysis using PKC alpha antibody against Hela (1), K562 (2), Jurkat (3), COS-7 (4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PKC alpha antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using PKC alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |