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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | 电询 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CyclinA antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CCNA1
Gene Synonyms
CT146
Gene Full Name
cyclin A1
Gene Summary
The protein encoded by this gene belongs
to the highly conserved cyclin family, whose members are characterized by a
dramatic periodicity in protein abundance through the cell cycle. Cyclins
function as regulators of CDK kinases. Different cyclins exhibit distinct
expression and degradation patterns which contribute to the temporal
coordination of each mitotic event. The cyclin encoded by this gene was shown
to be expressed in testis and brain, as well as in several leukemic cell
lines, and is thought to primarily function in the control of the germline
meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give
two distinct kinase activities, one appearing in S phase, the other in G2,
and thus regulate separate functions in cell cycle. This cyclin was found to
bind to important cell cycle regulators, such as Rb family proteins,
transcription factor E2F-1, and the p21 family proteins. Multiple transcript
variants encoding different isoforms have been found for this gene. [provided
by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
49 kDa
Source
Rabbit
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using CyclinA antibody against A549 (1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded laryngeal cancer tissues using CyclinA antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of HepG2 cells using CyclinA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |