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- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-08-16
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-FAS antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FAS
Gene Synonyms
APT1
CD95
FAS1
APO-1
FASTM
ALPS1A
TNFRSF6
Hide
Gene Full Name
Fas cell surface death receptor
Gene Summary
The protein encoded by this gene is a
member of the TNF-receptor superfamily. This receptor contains a death
domain. It has been shown to play a central role in the physiological
regulation of programmed cell death, and has been implicated in the
pathogenesis of various malignancies and diseases of the immune system. The
interaction of this receptor with its ligand allows the formation of a
death-inducing signaling complex that includes Fas-associated death domain
protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of
the caspases in the complex triggers a downstream caspase cascade, and leads
to apoptosis. This receptor has been also shown to activate NF-kappaB,
MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the
proliferating signals in normal diploid fibroblast and T cells. Several
alternatively spliced transcript variants have been described, some of which
are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking
the transmembrane domain may negatively regulate the apoptosis mediated by
the full length isoform. [provided by RefSeq, Mar 2011]
Hide
Molecular
Weight(MW)
38 kDa
Source
Rabbit
Cellular
Localizatio
Secreted and Cell membrane.
Application
·
WB
Western blot
analysis using FAS antibody against A431 (1) cell lysate.
· 
ICC/IF
Immunofluorescence
analysis of T24 cells using FAS (green). Blue: DAPI fluorescent DNA dye. Red:
Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-FAS antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FAS
Gene Synonyms
APT1
CD95
FAS1
APO-1
FASTM
ALPS1A
TNFRSF6
Hide
Gene Full Name
Fas cell surface death receptor
Gene Summary
The protein encoded by this gene is a
member of the TNF-receptor superfamily. This receptor contains a death
domain. It has been shown to play a central role in the physiological
regulation of programmed cell death, and has been implicated in the
pathogenesis of various malignancies and diseases of the immune system. The
interaction of this receptor with its ligand allows the formation of a
death-inducing signaling complex that includes Fas-associated death domain
protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of
the caspases in the complex triggers a downstream caspase cascade, and leads
to apoptosis. This receptor has been also shown to activate NF-kappaB,
MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the
proliferating signals in normal diploid fibroblast and T cells. Several
alternatively spliced transcript variants have been described, some of which
are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking
the transmembrane domain may negatively regulate the apoptosis mediated by
the full length isoform. [provided by RefSeq, Mar 2011]
Hide
Molecular
Weight(MW)
38 kDa
Source
Rabbit
Cellular
Localizatio
Secreted and Cell membrane.
Application
·
WB
Western blot
analysis using FAS antibody against A431 (1) cell lysate.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using FAS (green). Blue: DAPI fluorescent DNA dye. Red:
Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-FAS antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FAS
Gene Synonyms
APT1
CD95
FAS1
APO-1
FASTM
ALPS1A
TNFRSF6
Hide
Gene Full Name
Fas cell surface death receptor
Gene Summary
The protein encoded by this gene is a
member of the TNF-receptor superfamily. This receptor contains a death
domain. It has been shown to play a central role in the physiological
regulation of programmed cell death, and has been implicated in the
pathogenesis of various malignancies and diseases of the immune system. The
interaction of this receptor with its ligand allows the formation of a
death-inducing signaling complex that includes Fas-associated death domain
protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of
the caspases in the complex triggers a downstream caspase cascade, and leads
to apoptosis. This receptor has been also shown to activate NF-kappaB,
MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the
proliferating signals in normal diploid fibroblast and T cells. Several
alternatively spliced transcript variants have been described, some of which
are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking
the transmembrane domain may negatively regulate the apoptosis mediated by
the full length isoform. [provided by RefSeq, Mar 2011]
Hide
Molecular
Weight(MW)
38 kDa
Source
Rabbit
Cellular
Localizatio
Secreted and Cell membrane.
Application
·
WB
Western blot
analysis using FAS antibody against A431 (1) cell lysate.
·
ICC/IF
Immunofluorescence
analysis of T24 cells using FAS (green). Blue: DAPI fluorescent DNA dye. Red:
Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-FAS antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FAS
Gene Synonyms
APT1
Hide
Gene Full Name
Fas cell surface death receptor
Gene Summary
The protein encoded by this gene is a
member of the TNF-receptor superfamily. This receptor contains a death
domain. It has been shown to play a central role in the physiological
regulation of programmed cell death, and has been implicated in the
pathogenesis of various malignancies and diseases of the immune system. The
interaction of this receptor with its ligand allows the formation of a
death-inducing signaling complex that includes Fas-associated death domain
protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of
the caspases in the complex triggers a downstream caspase cascade, and leads
to apoptosis. This receptor has been also shown to activate NF-kappaB,
MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the
proliferating signals in normal diploid fibroblast and T cells. Several
alternatively spliced transcript variants have been described, some of which
are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking
the transmembrane domain may negatively regulate the apoptosis mediated by
the full length isoform. [provided by RefSeq, Mar 2011]
Hide
Molecular
Weight(MW)
38 kDa
Source
Rabbit
Cellular
Localizatio
Secreted and Cell membrane.
Application
ICC/IF:1:100-1:500
CD95
FAS1
APO-1
FASTM
ALPS1A
TNFRSF6
·
WB
Western blot analysis using FAS antibody against A431 (1) cell lysate.
·
ICC/IF
Immunofluorescence analysis of T24 cells using FAS (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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