Product Profile

Product Name	Anti-NTRK2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	NTRK2
Gene Synonyms	OBHD TRKB DEE58 trk-B EIEE58 GP145-TrkB Hide
Gene Full Name	neurotrophic receptor tyrosine kinase 2
Gene Summary	This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Hide
Molecular Weight(MW)	115kDa（Observed:92 kDa）
Source	Rabbit
Cellular Localizatio	Membrane

Application

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WB

Western blot analysis using NTRK2 antibody against Rb-1 (1), WM35 (2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using NTRK2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of T24 cells using NTRK2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.