Product Profile

Product Name	Anti-TBK1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	84 mg/ml
Purification	Protein A

Target Information

Gene Symbol	TBK1
Gene Synonyms	NAK T2K IIAE8 FTDALS4 Hide
Gene Full Name	TANK binding kinase 1
Gene Summary	The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010] Hide
Molecular Weight(MW)	84 kDa
Source	Rabbit
Cellular Localizatio	Cytoplasm

Application

·        

WB

Western blot analysis using TBK1 antibody against Caco-2 (1) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TBK1 antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of SK-OV-3 cells using TBK1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.