Product Name

Anti-PGC1 alpha antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Gene Symbol

PPARGC1A

Gene Synonyms

LEM6
PGC1
PGC1A
PGC-1v
PPARGC1
PGC-1alpha
PGC-1(alpha)

Hide 

Gene Full Name

PPARG coactivator 1 alpha

Gene Summary

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]

Hide 

Molecular Weight(MW)

91 kDa

Source

Rabbit

Cellular Localizatio

Cytoplasm. Nucleus; Nucleus and Nucleus. Nucleus; PML body

Application Notes

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.